In view of the recent reproducibility and predictability crisis in biomedical science, our aim is to establish a network which will work to refine, harmonise and promote data, documents and 3Rs concepts to improve the quality of preclinical research.
The development and introduction of new, powerful concepts for biomedical research is essential to reduce the production of non-reproducible and non-predictive data. This has immense scientific, economic and social significance. In this context, we propose that the findings and concepts from the 3Rs field can greatly help to greatly improve biomedical research on several levels.